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Information on the latest vitamin D news and research.

Find out more information on deficiency, supplementation, sun exposure, and how vitamin D relates to your health.

Vitamin D deficiency accelerates hardening of the arteries

Atherosclerosis is a chronic inflammation of the artery wall caused by the accumulation of white blood cells (macrophages) and lipids (LDL) in the wall. It is commonly referred to as a hardening of the arteries. Oxidized LDL molecules trigger a cascade of immune responses which over time can produce a plaque. The plaque causes the muscle cells to enlarge, forming a hard cover over the affected area, reducing blood flow. Some of the cells in the artery, the endoplasmic reticulum cells, have a stress activation pathway that is increasingly recognized as a crucial factor in the development of atherosclerosis.

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About John Cannell, MD

Dr. John Cannell is founder of the Vitamin D Council. He has written many peer-reviewed papers on vitamin D and speaks frequently across the United States on the subject. Dr. Cannell holds an M.D. and has served the medical field as a general practitioner, emergency physician, and psychiatrist.

2 Responses to Vitamin D deficiency accelerates hardening of the arteries

  1. Hypertension reduced in mice on high fat diet by adding vitamin D for 6 weeks– Jan 2013
    http://www.vitamindwiki.com/tiki-index.php?page_id=3706
    which is the same article that the Council described.

    Another mouse and vitamin D study
    Vitamin D was important during mouse pregnancy – wonder about human pregnancy.
    “Higher weight and blood pressure in second generation from mother mouse who had low vitamin D” http://www.vitamindwiki.com/tiki-index.php?page_id=3793

    60+ hypertension and vitamin D articles are located at:
    http://www.vitamindwiki.com/Hypertension

  2. sagefemme60 says:

    What about the role of calcium deposits within arterial walls and Atherosclerosis?
    Since vitamin D increases the absorption of calcium, might Vitamin K2 play a role in reducing atherosclerosis through directing calcium from arteries to bones and teeth?

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